Tags: Protein.

Rhotekin is a protein that in humans is encoded by the RTKN gene.This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes including cytokinesis transcription smooth muscle contraction cell growth and transformation.

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