Tags: Chemical Compound, Chemical Substance.

Roseophilin is an antibiotic isolated from Streptomyces griscovirides shown to have antitumor activity. The chemical structure can be considered in terms of two components a macrotricyclic segment and a heterocyclic side-chain. Several laboratory syntheses of roseophilin (e.g. those of Trost Furstner Salamone) are based upon the Paal-Knorr synthesis and two others are based on the Nazarov cyclization reaction (those of Tius Frontier).

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IUPAC name
15-[5-(3-Chloro-1H-pyrrol-2-yl)-3-methoxy-furan-2-yl]-13-isopropyl-2-aza-tricyclo[10.2.1.1314]hexadeca-1(15)2-triene

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