Tags: Protein.
ROCK1 is a protein serine/threonine kinase also known as rho-associated coiled-coil-containing protein kinase 1. Other common names are ROKβ and P160ROCK. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation. ROCK1 plays a role in cancer and in particular cell motility metastasis and angiogenesis.