Tags: Protein.
E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene.The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. Yeast BRE1 is a ubiquitin ligase required for the ubiquitination of histone H2B and the methylation of histone H3.