Tags: Protein.
Regulator of G-protein signaling 3 is a protein that in humans is encoded by the RGS3 gene.This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described but its sequence has not been identified.