Tags: Disease.
Reynolds syndrome is a rare secondary laminopathy consisting of the combination of primary biliary cirrhosis and progressive systemic sclerosis. In some patients this syndrome has also been associated with Sjögren’s syndrome and hemolytic anemia. Typical clinical features include jaundice elevated blood levels of alkaline phosphatase calcinosis cutis telangiectasias and pruritus. This disease may cause white or yellow-ish spots on the arms or legs.