Tags: Protein.
Negative elongation factor E is a protein that in humans is encoded by the RDBP gene.The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues largely arginine (R) and aspartic acid (D).