Tags: Drug.
Rasburicase (brand names: Elitek in the US and Fasturtec in Europe) is a recombinant version of urate oxidase an enzyme that metabolizes uric acid to allantoin. Urate oxidase is known to be present in many mammals but does not naturally occur in humans. Rasburicase is produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.Rasburicase is a tetrameric protein with identical subunits.
