Tags: Protein.
RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein) also known as RASA1 is a 120-kDa cytosolic human protein that provides two principal activities: Inactivation of Ras from its active GTP-bound form to its inactive GDP-bound form by enhancing the endogenous GTPase activity of Ras via its C-terminal GAP domain Mitogenic signal transmission towards downstream interacting partners through its N-terminal SH2-SH3-SH2 domainsThe protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins.