Tags: Protein.
Not to be confused with RANK the osteoclast cell-surface receptor that binds to RANKL.Receptor activator of nuclear factor kappa-B ligand (RANKL) also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11) TNF-related activation-induced cytokine (TRANCE) osteoprotegerin ligand (OPGL) and osteoclast differentiation factor (ODF) is a protein that in humans is encoded by the TNFSF11 gene.Critical for adequate bone metabolism this surface-bound molecule (also known as CD254) found on osteoblasts serves to activate osteoclasts which are the cells involved in bone resorption.