Tags: Disease.
Raine syndrome (RNS) also called osteosclerotic bone dysplasia is a rare autosomal recessive congenital disorder characterized by craniofacial anomalies including microcephaly noticeably low set ears osteroclerosis a cleft palate gum hyperplasia a hypoplastic nose and eye proptosis. It is considered to be a lethal disease and usually leads to death within a few hours of birth.