Tags: Protein.
Rab5 GDP/GTP exchange factor is a protein that in humans is encoded by the RABGEF1 gene.RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion and it serves as a specific guanine nucleotide exchange factor for RAB5 (RAB5A; MIM 179512) (Horiuchi et al. 1997).[supplied by OMIM]