Quinupristin is an antibiotic often used in combination with dalfopristin under the trade name Synercid. It is active against Gram-positive bacteria atypical but not Gram negatives. They inhibit protein synthesis of the cells.Quinupristin & dalfopristin are not active against Enterococcus faecalis and they need to be given in combination with other antibacterials for mixed infections which also involve Gram negative organisms.
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