Quadazocine (WIN-44441) is an opioid antagonist of the benzomorphan family which is used in scientific research. It acts as a silent antagonist at all three of the major opioid receptors—μ κ and δ but with a significant preference in affinity for the μ receptor and the κ2 subtype. As such it has been touted as a κ2-selective antagonist though of course this is not entirely accurate on account of its similar affinity for the μ receptor.
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