Tags: Disease.
Pulmonary alveolar proteinosis (abbreviated PAP) is a rare lung disease in which abnormal accumulation of surfactant occurs within the alveoli interfering with gas exchange. PAP can occur in a primary form or secondarily in the settings of malignancy (especially in myeloid leukemia) pulmonary infection or environmental exposure to dusts or chemicals. Rare familial forms have also been recognized suggesting a genetic component in some cases.
