Tags: Protein.
Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene.The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53 and may be involved in TP53-induced apoptosis.