Tags: Protein.
Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein.