Tags: Drug.
Prothrombin complex concentrate (PCC trade names Beriplex Ocplex Kcentra Cofact among others) is a combination of blood clotting factors II VII IX and X as well as protein C and S prepared from fresh-frozen human blood plasma. It is used to reverse the effects of oral anticoagulation therapy when bleeding occurs (e.g. in the brain or gut) requiring rapid action to accelerate coagulation. PCC is effective but expensive.