Tags: Drug.
N-n-Propylnorapomorphine (NPA) is an aporphine derivative dopamine agonist closely related to apomorphine. In rodents it has been shown to produce hyperactivity stereotypy hypothermia antinociception and penile erection among other effects. Notably its effects on locomotion are biphasic with low doses producing inhibition and catalepsy and high doses resulting in enhancement of activity.