Tags: Enzyme.
Procollagen-proline dioxygenase commonly known as prolyl hydroxylase is a member of the class of enzymes known as 2-oxoglutarate-dependent dioxygenases. These enzymes catalyze the incorporation of oxygen into organic substrates through a mechanism that requires 2-oxoglutarate Fe2+ and ascorbate. This particular enzyme catalyzes the formation of (2S 4R)-4-hydroxyproline a compound that represents the most prevalent post-translational modification in the human proteome.
