Tags: Protein.
Thioredoxin-dependent peroxide reductase mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene.This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide.