Tags: Enzyme.
Polynucleotide Phosphorylase (PNPase) is a bifunctional enzyme with a phosphorolytic 3′ to 5′ exoribonuclease activity and a 3′-terminal oligonucleotide polymerase activity. That is it dismantles the RNA chain starting at the 3′ end and working toward the 5′ end. It also synthesizes long highly heteropolymeric tails in vivo.
