Tags: Drug.
PNU-22394 is a drug which acts as an agonist at serotonin 5-HT2 receptors with strongest binding affinity for 5-HT2A and 5-HT2C and slightly weaker at 5-HT2B although it is only a full agonist at 5-HT2C but partial agonist at 5-HT2A and 5-HT2B. It has anorectic effects in both animal studies and human trials although it has never been developed for medical use.