Tags: Protein.
PMS1 protein homolog 1 is a protein that in humans is encoded by the PMS1 gene.The protein encoded by this gene was identified by its homology to a yeast protein involved in DNA mismatch repair. A role for this protein in mismatch repair has not been proven. However the protein forms heterodimers with MLH1 a DNA mismatch repair protein and some cases of hereditary nonpolyposis colorectal cancer have been found to have mutations in this gene.