Tags: Chemical Compound, Chemical Substance.
Pleuromutilin and its derivatives are antibacterial drugs that inhibit protein synthesis in bacteria by binding to the peptidyl transferase component of the 50S subunit of ribosomes.This class of antibiotics includes retapamulin (licenced for topical use in humans) valnemulin and tiamulin (approved for use in animals) and the investigational drugs azamulin and BC-3781.