Tags: Drug.

Pirarubicin (INN) is an anthracycline drug.An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.

Pirarubicin.png
ATC prefix
L01
ATC suffix
DB08
CAS number
72496-41-4
FDA UNII code
D58G680W0G
IUPAC name
(3S)-3-glycoloyl-3512-trihydroxy-10-methoxy-611-dioxo-1234611-hexahydrotetracen-1-yl 3-amino-236-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-(L)-lyxo-hexopyranoside
PubChem
3033521

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