Physostigmine (also known as eserine from éséré West African name for the Calabar bean) is a parasympathomimetic alkaloid specifically a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean.The chemical was synthesized for the first time in 1935 by the chemists Percy Lavon Julian and Josef Pikl. It is available in the U.S. under the trade names Antilirium Eserine Salicylate Isopto Eserine and Eserine Sulfate.
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