Tags: Chemical Compound, Chemical Substance.
Philanthotoxins are components of the venom of Egyptian solitary wasp Philanthus triangulum F and four toxins are distinguished (alpha beta gamma delta) among which delta-philanthotoxin (dPTX) is most effective to block glutamate receptors and especially those quisqualate-sensitive that is AMPA receptor. It has later been shown that dPTX targets calcium permeable AMPA receptor and kainate receptor but not NMDA receptor.