Phenoperidine was discovered by Janssen Pharmaceutica 1960. Marketed as its hydrochloride as Operidine or Lealgin is an opioid used as a general anesthetic. It is a derivative of isonipecotic acid like pethidine and is metabolized in part to norpethidine. It is 20-200 times as potent as pethidine as an analgesic.
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