Tags: Disease.
Perlman syndrome (PS) (also called renal hamartomas nephroblastomatosis and fetal gigantism) is a rare overgrowth disorder present at birth. It is characterized by polyhydramnios and fetal overgrowth including macrocephaly neonatal macrosomia visceromegaly dysmorphic facial features and an increased risk for Wilms’ tumor at an early age. The prognosis for Perlman syndrome is poor and it is associated with a high neonatal mortality.