Tags: Disease.
A peptic ulcer is a distinct breach in the mucosal lining of the stomach (gastric ulcer) or the first part of the small intestine (duodenal ulcer) a result of caustic effects of acid and pepsin in the lumen. Histologically peptic ulcer is identified as necrosis of the mucosa which produces lesions equal to or greater than 0.5 cm (1/5). It is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful.