Tags: Drug.
Pentylenetetrazol (INN) also known as pentylenetetrazole metrazol pentetrazol pentamethylenetetrazol Cardiazol or PTZ was a drug used as a circulatory and respiratory stimulant. High doses cause convulsions as discovered by the Hungarian-American neurologist and psychiatrist Ladislas J. Meduna in 1934. It has been used in convulsive therapy but was never considered to be effective and side-effects such as seizures were difficult to avoid. Its approval by the FDA was revoked in 1982.