Tags: Protein.
Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1) is a multifunctional secreted protein that has anti-angiogenic anti-tumorigenic and neurotrophic functions. Found in vertebrates this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as choroidal neovascularization heart disease and cancer. In humans pigment epithelium-derived factor is encoded by the SERPINF1 gene.