Tags: Protein.
Rod cGMP-specific 3’5′-cyclic phosphodiesterase subunit beta is an enzyme that in humans is encoded by the PDE6B gene.Mice homozygous for the rd mutation display hereditary retinal degeneration which has been considered a model for human retinitis pigmentosa. In affected animals the retinal rod photoreceptor cells begin degenerating at about postnatal day 8 and by 4 weeks no photoreceptors are left.