Tags: Protein.
Presenilins-associated rhomboid-like protein mitochondrial is a protein that in humans is encoded by the PARL gene. It is a member of the rhomboid family of intramembrane serine proteases.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins.