Tags: Biological Database, Database.
PANAV (Probabilistic Approach for protein NMR Assignment Validation) is a freely available stand-alone program that is used for protein chemical shift re-referencing [1]. Chemical shift referencing is a problem in protein NMR as >20% of reported NMR chemical shift assignments appear to be improperly referenced [1]. For certain nuclei (especially 13C and 15N) these referencing issues can cause systematic chemical shift errors of between 1.0 to 2.5 ppm.