Tags: Drug.

Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a US National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree Taxus brevifolia and named it taxol.

Taxol.svg
ATC prefix
L01
ATC suffix
CD01
ATC supplemental
(paclitaxel poliglumex)
Bioavailability
6.5
CAS number
33069-62-4
ChEBI
45863
DrugBank
DB01229
FDA UNII code
P88XT4IS4D
IUPAC name
(2α4α5β7β10β13α)-410-bis(acetyloxy)-13-[(2R3S)- 3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy- 17-dihydroxy-9-oxo-520-epoxytax-11-en-2-yl benzoate
PubChem
36314

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