Tags: Protein.
p16 (also known as cyclin-dependent kinase inhibitor 2A multiple tumor suppressor 1 and as several other synonyms) is a tumor suppressor protein that in humans is encoded by the CDKN2A gene. p16 plays an important role in cell cycle regulation by decelerating cells progression from G1 phase to S phase and therefore acts as a tumor suppressor that is implicated in the prevention of cancers notably melanoma oropharyngeal squamous cell carcinoma and esophageal cancer.