Tags: Drug.
Osemozotan (MKC-242) is a selective 5-HT1A receptor agonist with some functional selectivity acting as a full agonist at presynaptic and a partial agonist at postsynaptic 5-HT1A receptors. It has antidepressant and anxiolytic effects in animal studies and is used to investigate the role of 5-HT1A receptors in modulating the release of dopamine and serotonin in the brain and their involvement in addiction to abused stimulants such as cocaine and methamphetamine.
