Tags: Chemical Compound, Chemical Substance.
Ortho-DOT or 45-dimethoxy-2-methylthioamphetamine is a lesser-known psychedelic drug. Ortho-DOT was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved) neither the dosage nor the duration are known. Ortho-DOT produces few to no effects. Very little data exists about the pharmacological properties metabolism and toxicity of Ortho-DOT.