Tags: Chemical Compound, Chemical Substance.
Orteronel (TAK-700) is an experimental drug for the treatment of cancer discovered by Takeda Pharmaceutical Company and under development by Millennium Pharmaceuticals. It is currently in Phase III clinical trials for metastatic hormone-refractory prostate cancer.Orteronel is an androgen synthesis inhibitor. It selectively inhibits the enzyme CYP17A1 which is expressed in testicular adrenal and prostatic tumor tissues.