Tags: Drug.
O-2172 is a drug developed by Organix Inc which acts as a stimulant and potent dopamine reuptake inhibitor. It is an analogue of methylphenidate where the phenyl ring has had a 34-dichloro substitution added and the piperidine ring has been replaced by cyclopentane. It is around 1/3 the potency of methylphenidate demonstrating that even with the important binding group of the nitrogen lone pair removed entirely selective DAT binding and reuptake inhibition is still possible.
