Tags: Protein.
RNA-binding protein Nova-1 is a protein that in humans is encoded by the NOVA1 gene.This gene encodes a neuron-specific RNA-binding protein a member of the Nova family of paraneoplastic disease antigens that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia breast cancer and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.