Tags: Protein.
NACHT LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene.NALP proteins such as NALP2 are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al. 2003).[supplied by OMIM]