Tags: Chemical Compound, Chemical Substance.

Nigericin is an antibiotic derived from Streptomyces hygroscopicus. Its isolation was described in the 1950s and in 1968 the structure could be elucidated by X-ray crystallography. The structure and properties of nigericin are similar to the antibiotic monensin. Commercially it is obtained as a byproduct or contaminant at the fermentation of Geldanamycin. It is also called Polyetherin A Azalomycin M Helixin C Antibiotic K178 Antibiotic X-464.Nigericin acts as an H+ K+ Pb2+ ionophore.

Nigericin.svg
IUPAC name
2-tetrahydrofuranyl]-5-methyl-2-tetrahydrofuranyl]-9-methoxy-, 2410-trimethyl-16-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyl-, 2-tetrahydropyranyl]propanoic acid, (2R)-2-[(2R3S6R)-6-[[(2S4R5R7R9R10R)-]2-[(2R5S)-5-[(2R3S5R)-5-[(2S3S5R6R)-6-hydroxy-]6-(hydroxymethyl)-35-dimethyl-2-tetrahydropyranyl]-3-methyl-

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