Tags: Chemical Compound, Chemical Substance.

Nepicastat (INN codenamed SYN117 RS-25560-197) is an inhibitor of dopamine beta-hydroxylase an enzyme that catalyzes the conversion of dopamine to norepinephrine.It has been studied as a possible treatment for congestive heart failure and appears to be well tolerated as such. As of 2012 clinical trials to assess nepicastat as a treatment for post-traumatic stress disorder (PTSD) and cocaine dependence have been completed.

Nepicastat.png
FDA UNII code
VPG12K4540
IUPAC name
5-(aminomethyl)-1-[(2S)-57-difluoro-1234-tetrahydronaphthalen-2-yl]-13-dihydro-2H-imidazole-2-thione

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