Tags: Chemical Compound, Chemical Substance.
Neopterin is a catabolic product of guanosine triphosphate (GTP) a purine nucleotide. Neopterin belongs to the chemical group known as pteridines. It is synthesised by human macrophages upon stimulation with the cytokine interferon-gamma and is indicative of a pro-inflammatory immune status. Neopterin serves as a marker of cellular immune system activation.
