Tags: Disease.
Neonatal cholestasis defines persisiting conjugated hyperbilirubinemia in the newborn with conjugated bilirubin levels exceeding 15% (5.0 mg/dL) of total bilirubin level. The disease is either due to defects in bile excretion from hepatocytes or impaired bile flow.General presentations in neonates include abdominal pain and general GI upset.