Tags: Protein.
Endonuclease VIII-like 1 is an enzyme that in humans is encoded by the NEIL1 gene.NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al. 2002).[supplied by OMIM]