Tags: Chemical Compound, Chemical Substance.
NBQX (23-dihydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxaline-23-dione) is an AMPA receptor antagonist.NBQX blocks AMPA receptors in micromolar concentrations (~10–20 µM) and also blocks kainate receptors. In experiments it is used to counter glutamate excitotoxicity. NBQX was found to have anticonvulsant activity in rodent seizure models.As the disodium salt NBQX is soluble in water at high concentrations (at least up to 100 mM).
